CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
Superfamily | Vaccinia Virus protein VP39 |
Functional Family | Phenylethanolamine N-methyltransferase |
Enzyme Information
2.1.1.28 |
Phenylethanolamine N-methyltransferase.
based on mapping to UniProt P11086
S-adenosyl-L-methionine + phenylethanolamine = S-adenosyl-L-homocysteine + N-methylphenylethanolamine.
-!- Acts on various phenylethanolamines; converts noradrenaline into adrenaline.
|
UniProtKB Entries (1)
P11086 |
PNMT_HUMAN
Homo sapiens
Phenylethanolamine N-methyltransferase
|
PDB Structure
PDB | 2OBF |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Enzyme Adaptation to Inhibitor Binding: A Cryptic Binding Site in Phenylethanolamine N-Methyltransferase
J.Med.Chem.
|