CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.970
Functional Family 1-deoxy-D-xylulose-5-phosphate synthase

Enzyme Information

2.2.1.7
1-deoxy-D-xylulose-5-phosphate synthase.
based on mapping to UniProt P77488
Pyruvate + D-glyceraldehyde 3-phosphate = 1-deoxy-D-xylulose 5-phosphate + CO(2).
-!- The enzyme forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis. -!- Formerly EC 4.1.3.37.

UniProtKB Entries (1)

P77488
DXS_ECOLI
Escherichia coli K-12
1-deoxy-D-xylulose-5-phosphate synthase

PDB Structure

PDB 2O1S
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structure of 1-Deoxy-D-xylulose 5-Phosphate Synthase, a Crucial Enzyme for Isoprenoids Biosynthesis.
Xiang, S., Usunow, G., Lange, G., Busch, M., Tong, L.
J.Biol.Chem.