1 keywords

CATH Domain 2n1fO00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.533 Death Domain, Fas
Homologous Superfamily 1.10.533.10 Death Domain, Fas

Domain Context

CATH Clusters

Superfamily Death Domain, Fas
Functional Family Apoptosis-associated speck-like protein containing a CARD

Enzyme Information

UniProtKB Entries (1)

Q9EPB4
ASC_MOUSE
Mus musculus
Apoptosis-associated speck-like protein containing a CARD

PDB Structure

PDB 2N1F
External Links
Method SOLID-STATE NMR
Organism
Primary Citation
Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy.
Sborgi, L., Ravotti, F., Dandey, V.P., Dick, M.S., Mazur, A., Reckel, S., Chami, M., Scherer, S., Huber, M., Bockmann, A., Egelman, E.H., Stahlberg, H., Broz, P., Meier, B.H., Hiller, S.
Proc.Natl.Acad.Sci.USA