CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.870 | DHBP synthase |
|
3.90.870.10 | DHBP synthase |
Domain Context
CATH Clusters
| Superfamily | DHBP synthase |
| Functional Family | Threonylcarbamoyl-AMP synthase |
Enzyme Information
| 2.7.7.87 |
L-threonylcarbamoyladenylate synthase.
based on mapping to UniProt P45748
L-threonine + ATP + HCO(3)(-) = L-threonylcarbamoyladenylate + diphosphate + H(2)O.
-!- The enzyme is involved in the synthesis of N(6)- threonylcarbamoyladenosine(37) in tRNAs with the anticodon NNU, i.e. tRNA(Ile), tRNA(Thr), tRNA(Asn), tRNA(Lys), tRNA(Ser) and tRNA(Arg).
|
UniProtKB Entries (1)
| P45748 |
TSAC_ECOLI
Escherichia coli K-12
Threonylcarbamoyl-AMP synthase
|
PDB Structure
| PDB | 2MX1 |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
NMR-based Structural Analysis of Threonylcarbamoyl-AMP Synthase and Its Substrate Interactions.
J.Biol.Chem.
|