CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.20 | Single Sheet |
|
2.20.70 | Ubiquitin Ligase Nedd4; Chain: W; |
|
2.20.70.10 |
Domain Context
CATH Clusters
| Superfamily | 2.20.70.10 |
| Functional Family |
Enzyme Information
| 2.1.1.- |
Methyltransferases.
based on mapping to UniProt Q9BYW2
|
| 2.1.1.43 |
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q9BYW2
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
|
UniProtKB Entries (1)
| Q9BYW2 |
SETD2_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase SETD2
|
PDB Structure
| PDB | 2MDI |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Autoinhibitory structure of the WW domain of HYPB/SETD2 regulates its interaction with the proline-rich region of huntingtin.
Structure
|