CATH Classification

Domain Context

CATH Clusters

Superfamily Rieske [2Fe-2S] iron-sulphur domain
Functional Family Nitrite reductase [NAD(P)H] small subunit

Enzyme Information

1.7.1.15
Nitrite reductase (NADH).
based on mapping to UniProt P0A9I8
Ammonia + 3 NAD(+) + 2 H(2)O = nitrite + 3 NADH.
-!- This prokaryotic enzyme is specific for NADH. -!- In addition to catalyzing the 6-electron reduction of nitrite to ammonia, the enzyme from Escherichia coli can also catalyze the 2-electron reduction of hydroxylamine to ammonia. -!- cf. EC 1.7.1.4.

UniProtKB Entries (1)

P0A9I8
NIRD_ECOLI
Escherichia coli K-12
Nitrite reductase (NADH) small subunit

PDB Structure

PDB 2JO6
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
NMR structure of E.coli NirD.
Ramelot, T.A., Cort, J.R., Yee, A.A., Arrowsmith, C.H., Kennedy, M.A.
To be Published