CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family Lipase

Enzyme Information

3.1.1.32
Phospholipase A(1).
based on mapping to UniProt P04635
Phosphatidylcholine + H(2)O = 2-acylglycerophosphocholine + a carboxylate.
-!- Has a much broader specificity than EC 3.1.1.4.
3.1.1.3
Triacylglycerol lipase.
based on mapping to UniProt P04635
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
-!- The pancreatic enzyme acts only on an ester-water interface; the outer ester links are preferentially hydrolyzed.

UniProtKB Entries (1)

P04635
LIP_STAHY
Staphylococcus hyicus
Lipase

PDB Structure

PDB 2HIH
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis of phospholipase activity of Staphylococcus hyicus lipase.
Tiesinga, J.J., van Pouderoyen, G., Nardini, M., Ransac, S., Dijkstra, B.W.
J.Mol.Biol.