CATH Classification

Domain Context

CATH Clusters

Superfamily Glutathione synthase, substrate-binding domain superfamily, eukaryotic
Functional Family Glutathione synthetase

Enzyme Information

6.3.2.3
Glutathione synthase.
based on mapping to UniProt P48637
ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione.

UniProtKB Entries (1)

P48637
GSHB_HUMAN
Homo sapiens
Glutathione synthetase

PDB Structure

PDB 2HGS
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Molecular basis of glutathione synthetase deficiency and a rare gene permutation event.
Polekhina, G., Board, P.G., Gali, R.R., Rossjohn, J., Parker, M.W.
EMBO J.