CATH Classification

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family Phosphoadenosine phosphosulfate reductase

Enzyme Information

1.8.4.8
Phosphoadenylyl-sulfate reductase (thioredoxin).
based on mapping to UniProt O05927
Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin.
-!- Specific for PAPS. -!- The enzyme from Escherichia coli will use thioredoxins from other species. -!- Formerly EC 1.8.99.4.

UniProtKB Entries (1)

O05927
CYSH_PSEAE
Pseudomonas aeruginosa PAO1
Phosphoadenosine phosphosulfate reductase

PDB Structure

PDB 2GOY
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Substrate Recognition, Protein Dynamics, and Iron-Sulfur Cluster in Pseudomonas aeruginosa Adenosine 5'-Phosphosulfate Reductase.
Chartron, J., Carroll, K.S., Shiau, C., Gao, H., Leary, J.A., Bertozzi, C.R., Stout, C.D.
J.Mol.Biol.