CATH Classification

Domain Context

CATH Clusters

Superfamily Isopropylmalate Dehydrogenase
Functional Family 3-isopropylmalate dehydrogenase

Enzyme Information

1.1.1.85
3-isopropylmalate dehydrogenase.
based on mapping to UniProt P9WKK9
(2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO(2) + NADH.

UniProtKB Entries (1)

P9WKK9
LEU3_MYCTU
Mycobacterium tuberculosis H37Rv
3-isopropylmalate dehydrogenase

PDB Structure

PDB 2G4O
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths.
Mueller-Dieckmann, C., Panjikar, S., Schmidt, A., Mueller, S., Kuper, J., Geerlof, A., Wilmanns, M., Singh, R.K., Tucker, P.A., Weiss, M.S.
Acta Crystallogr.,Sect.D