CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1000 | HAD superfamily/HAD-like |
Domain Context
CATH Clusters
| Superfamily | HAD superfamily/HAD-like |
| Functional Family | Histidine biosynthesis bifunctional protein HisB |
Enzyme Information
| 4.2.1.19 |
Imidazoleglycerol-phosphate dehydratase.
based on mapping to UniProt Q9S5G5
D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2- oxopropyl phosphate + H(2)O.
|
| 3.1.3.15 |
Histidinol-phosphatase.
based on mapping to UniProt Q9S5G5
L-histidinol phosphate + H(2)O = L-histidinol + phosphate.
|
UniProtKB Entries (1)
| Q9S5G5 |
HIS7_ECO57
Escherichia coli O157:H7
Histidine biosynthesis bifunctional protein HisB
|
PDB Structure
| PDB | 2FPX |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural snapshots of Escherichia coli histidinol phosphate phosphatase along the reaction pathway.
J.Biol.Chem.
|