CATH Classification

Domain Context

CATH Clusters

Superfamily ACT-like. Chain A, domain 2
Functional Family Acetolactate synthase small subunit

Enzyme Information

2.2.1.6
Acetolactate synthase.
based on mapping to UniProt P00894
2 pyruvate = 2-acetolactate + CO(2).
-!- The reaction shown is in the pathway of biosynthesis of valine. -!- The enzyme can also transfer the acetaldehyde from pyruvate to 2-oxobutanoate, forming 2-ethyl-2-hydroxy-3-oxobutanoate, also known as 2-aceto-2-hydroxybutanoate, a reaction in the biosynthesis of isoleucine. -!- Formerly EC 4.1.3.18.

UniProtKB Entries (1)

P00894
ILVH_ECOLI
Escherichia coli K-12
Acetolactate synthase isozyme 3 small subunit

PDB Structure

PDB 2F1F
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of the Regulatory Subunit of Acetohydroxyacid Synthase Isozyme III from Escherichia coli.
Kaplun, A., Vyazmensky, M., Zherdev, Y., Belenky, I., Slutzker, A., Mendel, S., Barak, Z., Chipman, D.M., Shaanan, B.
J.Mol.Biol.