CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family 17-beta-hydroxysteroid dehydrogenase 14

Enzyme Information

1.1.1.-
With NAD(+) or NADP(+) as acceptor.
based on mapping to UniProt Q9BPX1

UniProtKB Entries (1)

Q9BPX1
DHB14_HUMAN
Homo sapiens
17-beta-hydroxysteroid dehydrogenase 14

PDB Structure

PDB 1YDE
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity.
Lukacik, P., Keller, B., Bunkoczi, G., Kavanagh, K.L., Kavanagh, K., Lee, W.H., Hwa Lee, W., Adamski, J., Oppermann, U.
Biochem.J.