CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside phosphorylase domain
Functional Family Uridine phosphorylase

Enzyme Information

2.4.2.3
Uridine phosphorylase.
based on mapping to UniProt P0A1F6
Uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.
-!- The enzyme participates the the pathways of pyrimidine ribonucleosides degradation and salvage. -!- The mammalian enzyme also accepts 2'-deoxyuridine. -!- Formerly EC 2.4.2.23.

UniProtKB Entries (1)

P0A1F6
UDP_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Uridine phosphorylase

PDB Structure

PDB 1Y1S
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structures of Salmonella Typhimurium Uridine Phosphorylase in Native and Three Complexes Forms - with Uridine, Uracil and Sulfate.
Gabdoulkhakov, A.G., Dontsova, M.V., Kachalova, G.S., Betzel, C., Ealick, S.E., Mikhailov, A.M.
To be Published