CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.740 | Isoleucyl-tRNA Synthetase; domain 2 |
|
3.90.740.10 | Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain |
Domain Context
CATH Clusters
| Superfamily | Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain |
| Functional Family | Leucine--tRNA ligase |
Enzyme Information
| 6.1.1.4 |
Leucine--tRNA ligase.
based on mapping to UniProt O58698
ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).
|
UniProtKB Entries (1)
| O58698 |
SYL_PYRHO
Pyrococcus horikoshii OT3
Leucine--tRNA ligase
|
PDB Structure
| PDB | 1WZ2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The crystal structure of Leucyl-tRNA synthetase and tRNA(leucine) complex
to be published
|
