CATH Classification

Domain Context

CATH Clusters

Superfamily Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain
Functional Family Leucine--tRNA ligase

Enzyme Information

6.1.1.4
Leucine--tRNA ligase.
based on mapping to UniProt O58698
ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).

UniProtKB Entries (1)

O58698
SYL_PYRHO
Pyrococcus horikoshii OT3
Leucine--tRNA ligase

PDB Structure

PDB 1WZ2
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The crystal structure of Leucyl-tRNA synthetase and tRNA(leucine) complex
Fukunaga, R., Yokoyama, S.
to be published