CATH Classification

Domain Context

CATH Clusters

Superfamily Transcription Factor, Ets-1
Functional Family ephrin type-A receptor 8

Enzyme Information

2.7.10.1
Receptor protein-tyrosine kinase.
based on mapping to UniProt P29322
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- The receptor protein-tyrosine kinases, which can be defined as having a transmembrane domain, are a large and diverse multigene family found only in metazoans. -!- In the human genome, 58 receptor-type protein-tyrosine kinases have been identified and these are distributed into 20 subfamilies. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P29322
EPHA8_HUMAN
Homo sapiens
Ephrin type-A receptor 8

PDB Structure

PDB 1UCV
External Links
Method SOLUTION NMR
Organism
Primary Citation
NMR Structure of Sterile alpha motif (SAM) domain of ephrin type-A receptor 8
Goroncy, A., Kigawa, T., Koshiba, S., Kobayashi, N., Tochio, N., Inoue, M., Yokoyama, S.
To be Published