CATH Classification

Domain Context

CATH Clusters

Superfamily 2.40.40.20
Functional Family Biotin sulfoxide reductase 2

Enzyme Information

1.7.2.3
Trimethylamine-N-oxide reductase.
based on mapping to UniProt O87948
Trimethylamine + 2 (ferricytochrome c)-subunit + H(2)O = trimethylamine N-oxide + 2 (ferrocytochrome c)-subunit + 2 H(+).
-!- Contains bis(molybdopterin guanine dinucleotide)molybdenum cofactor. -!- The reductant is a membrane-bound multiheme cytochrome c. -!- Also reduces dimethyl sulfoxide to dimethyl sulfide.

UniProtKB Entries (1)

O87948
TORA_SHEMA
Shewanella massilia
Trimethylamine-N-oxide reductase

PDB Structure

PDB 1TMO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of oxidized trimethylamine N-oxide reductase from Shewanella massilia at 2.5 A resolution.
Czjzek, M., Dos Santos, J.P., Pommier, J., Giordano, G., Mejean, V., Haser, R.
J.Mol.Biol.