CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.40 | Beta Barrel | |
2.40.260 | Sortase; Chain: A; | |
2.40.260.10 | Sortase |
Domain Context
CATH Clusters
Superfamily | Sortase |
Functional Family | Class A sortase SrtA |
Enzyme Information
3.4.22.70 |
Sortase A.
based on mapping to UniProt Q9S446
The enzyme catalyzes a cell wall sorting reaction in which a surface protein with a sorting signal containing a LPXTG motif is cleaved between the Thr and Gly residue. The resulting threonine carboxyl end of the protein is covalently attached to a pentaglycine cross-bridge of peptidoglycan.
-!- Belongs to peptidase family C60.
|
UniProtKB Entries (1)
Q9S446 |
Q9S446_STAAU
Staphylococcus aureus
Class A sortase SrtA
|
PDB Structure
PDB | 1T2P |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
CRYSTAL STRUCTURES OF STAPHYLOCOCCUS AUREUS SORTASE A AND ITS SUBSTRATE COMPLEX
J.Biol.Chem.
|