CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.360 | Flavodoxin domain |
Domain Context
CATH Clusters
| Superfamily | 3.40.50.360 |
| Functional Family | NAD(P)H-dependent FMN reductase LOT6 |
Enzyme Information
| 1.5.1.39 |
FMN reductase (NAD(P)H).
based on mapping to UniProt Q07923
FMNH(2) + NAD(P)(+) = FMN + NAD(P)H.
-!- The enzyme can utilize NADH and NADPH with similar reaction rates. -!- Different from EC 1.5.1.42 and EC 1.5.1.38. -!- The luminescent bacterium Vibrio harveyi possesses all three enzymes, while the bacterium Aliivibrio fischeri contains only this non- specific type. -!- Also reduces riboflavin and FAD, but more slowly. -!- Formerly EC 1.5.1.29 and EC 1.6.8.1.
|
UniProtKB Entries (1)
| Q07923 |
LOT6_YEAST
Saccharomyces cerevisiae S288C
NAD(P)H-dependent FMN reductase LOT6
|
PDB Structure
| PDB | 1T0I |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal Structure and Functional Characterization of Yeast YLR011wp, an Enzyme with NAD(P)H-FMN and Ferric Iron Reductase Activities
J.Biol.Chem.
|