CATH Domain 1sczA00
|3.30.559.10||Chloramphenicol acetyltransferase-like domain|
|Superfamily||Chloramphenicol acetyltransferase-like domain|
|Functional Family||Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex|
based on mapping to UniProt P0AFG6
Succinyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)- (S-succinyldihydrolipoyl)lysine.
-!- A multimer (24-mer) of this enzyme forms the core of the multienzyme complex, and binds tightly both EC 18.104.22.168 and EC 22.214.171.124. -!- The lipoyl group of this enzyme is reductively succinylated by EC 126.96.36.199, and the only observed direction catalyzed by EC 188.8.131.52 is that where this succinyl group is passed to coenzyme A.
UniProtKB Entries (1)
Escherichia coli K-12
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex
Improved structural model for the catalytic domain of E.coli dihydrolipoamide succinyltransferase
To be Published