CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family Glutathione S-transferase

Enzyme Information

2.5.1.18
Glutathione transferase.
based on mapping to UniProt P0A9D2
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.

UniProtKB Entries (1)

P0A9D2
GSTA_ECOLI
Escherichia coli K-12
Glutathione S-transferase GstA

PDB Structure

PDB 1N2A
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Conserved structural elements in glutathione transferase homologues encoded in the genome of Escherichia coli
Rife, C.L., Parsons, J.F., Xiao, G., Gilliland, G.L., Armstrong, R.N.
Proteins