CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.20 | Up-down Bundle | |
1.20.1050 | Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 | |
1.20.1050.10 |
Domain Context
CATH Clusters
Superfamily | 1.20.1050.10 |
Functional Family | Transcriptional regulator URE2 |
Enzyme Information
1.8.4.- |
With a disulfide as acceptor.
based on mapping to UniProt P23202
|
1.11.1.9 |
Glutathione peroxidase.
based on mapping to UniProt P23202
2 glutathione + H(2)O(2) = glutathione disulfide + 2 H(2)O.
-!- Steroid and lipid hydroperoxides, but not the product of reaction of EC 1.13.11.12 on phospholipids, can act as acceptor, but more slowly than H(2)O(2) (cf. EC 1.11.1.12).
|
UniProtKB Entries (1)
P23202 |
URE2_YEAST
Saccharomyces cerevisiae S288C
Transcriptional regulator URE2
|
PDB Structure
PDB | 1JZR |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Crystal structures of the yeast prion Ure2p functional region in complex with glutathione and related compounds.
Biochemistry
|