CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family Lipase

Enzyme Information

3.1.1.3
Triacylglycerol lipase.
based on mapping to UniProt P07098
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
-!- The pancreatic enzyme acts only on an ester-water interface; the outer ester links are preferentially hydrolyzed.

UniProtKB Entries (1)

P07098
LIPG_HUMAN
Homo sapiens
Gastric triacylglycerol lipase

PDB Structure

PDB 1HLG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of human gastric lipase and model of lysosomal acid lipase, two lipolytic enzymes of medical interest.
Roussel, A., Canaan, S., Egloff, M.P., Riviere, M., Dupuis, L., Verger, R., Cambillau, C.
J.Biol.Chem.