CATH Classification

Domain Context

CATH Clusters

Superfamily 3.10.450.50
Functional Family calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1

Enzyme Information

2.7.11.17
Calcium/calmodulin-dependent protein kinase.
based on mapping to UniProt P11798
ATP + a protein = ADP + a phosphoprotein.
-!- Requires calmodulin. -!- A wide range of proteins can act as acceptor, including vimentin, synapsin, glycogen synthase, myosin light-chains and the microtubule- associated tau protein. -!- Not identical with EC 2.7.11.18 or EC 2.7.11.26. -!- Formerly EC 2.7.1.120 and EC 2.7.1.123.

UniProtKB Entries (1)

P11798
KCC2A_MOUSE
Mus musculus
Calcium/calmodulin-dependent protein kinase type II subunit alpha

PDB Structure

PDB 1HKX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of a Tetradecameric Assembly of the Association Domain of Ca2+/Calmodulin-Dependent Kinase II
Hoelz, A., Nairn, A.C., Kuriyan, J.
Mol.Cell