CATH Classification

Domain Context

CATH Clusters

Superfamily Phage p2 RNA dependent RNA polymerase domain
Functional Family

Enzyme Information

2.7.7.48
RNA-directed RNA polymerase.
based on mapping to UniProt P11124
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
-!- Catalyzes RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- See also EC 2.7.7.6.

UniProtKB Entries (1)

P11124
RDRP_BPPH6
Pseudomonas virus phi6
RNA-directed RNA polymerase

PDB Structure

PDB 1HHT
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A Mechanism for Initiating RNA-Dependent RNA Polymerization
Butcher, S.J., Grimes, J.M., Makeyev, E.V., Bamford, D.H., Stuart, D.I.
Nature