CATH Classification

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family Tyrosine-protein phosphatase non-receptor type

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P29350
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

P29350
PTN6_HUMAN
Homo sapiens
Tyrosine-protein phosphatase non-receptor type 6

PDB Structure

PDB 1GWZ
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the catalytic domain of protein-tyrosine phosphatase SHP-1.
Yang, J., Liang, X., Niu, T., Meng, W., Zhao, Z., Zhou, G.W.
J.Biol.Chem.