CATH Classification

Domain Context

CATH Clusters

Superfamily Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family Malate dehydrogenase

Enzyme Information

1.1.1.37
Malate dehydrogenase.
based on mapping to UniProt P0C890
(S)-malate + NAD(+) = oxaloacetate + NADH.
-!- Also oxidizes some other 2-hydroxydicarboxylic acids.
1.1.1.37
Malate dehydrogenase.
based on mapping to UniProt P80039
(S)-malate + NAD(+) = oxaloacetate + NADH.
-!- Also oxidizes some other 2-hydroxydicarboxylic acids.

UniProtKB Entries (2)

P80039
MDH_CHLTE
Chlorobaculum tepidum TLS
Malate dehydrogenase
P0C890
MDH_PROVB
Prosthecochloris vibrioformis
Malate dehydrogenase

PDB Structure

PDB 1GUZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis for Thermophilic Protein Stability: Structures of Thermophilic and Mesophilic Malate Dehydrogenases
Dalhus, B., Saarinen, M., Sauer, U.H., Eklund, P., Johansson, K., Karlsson, A., Ramaswamy, S., Bjork, A., Synstad, B., Naterstad, K., Sirevag, R., Eklund, H.
J.Mol.Biol.