CATH Classification

Domain Context

CATH Clusters

Superfamily Bira Bifunctional Protein; Domain 2
Functional Family DNA polymerase subunit gamma-2, mitochondrial

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q9QZM2
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

Q9QZM2
DPOG2_MOUSE
Mus musculus
DNA polymerase subunit gamma-2, mitochondrial

PDB Structure

PDB 1G5I
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure and deletion analysis show that the accessory subunit of mammalian DNA polymerase gamma, Pol gamma B, functions as a homodimer.
Carrodeguas, J.A., Theis, K., Bogenhagen, D.F., Kisker, C.
Mol.Cell