CATH Classification

Domain Context

CATH Clusters

Superfamily Histidine kinase-like ATPase, C-terminal domain
Functional Family Two-component sensor kinase EnvZ

Enzyme Information

2.7.13.3
Histidine kinase.
based on mapping to UniProt P0AEJ4
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
-!- This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine). -!- A number of histones can act as acceptor.

UniProtKB Entries (1)

P0AEJ4
ENVZ_ECOLI
Escherichia coli K-12
Osmolarity sensor protein EnvZ

PDB Structure

PDB 1BXD
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
NMR structure of the histidine kinase domain of the E. coli osmosensor EnvZ.
Tanaka, T., Saha, S.K., Tomomori, C., Ishima, R., Liu, D., Tong, K.I., Park, H., Dutta, R., Qin, L., Swindells, M.B., Yamazaki, T., Ono, A.M., Kainosho, M., Inouye, M., Ikura, M.
Nature