CATH Classification

Domain Context

CATH Clusters

Superfamily tRNA intron endonuclease, N-terminal domain
Functional Family tRNA-splicing endonuclease

Enzyme Information

4.6.1.16
tRNA-intron lyase.
based on mapping to UniProt Q58819
PretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.
-!- The enzyme catalyzes the final stage in the maturation of tRNA molecules. -!- Formerly EC 3.1.27.9.

UniProtKB Entries (1)

Q58819
ENDA_METJA
Methanocaldococcus jannaschii DSM 2661
TRNA-splicing endonuclease

PDB Structure

PDB 1A79
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure and evolution of a transfer RNA splicing enzyme.
Li, H., Trotta, C.R., Abelson, J.
Science