The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Thyroglobulin type-1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 1307: Secreted modular calcium-binding 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q9H4F8 (/IPI) Q9H4F8 (/IPI)
Glycosaminoglycan binding GO:0005539
Interacting selectively and non-covalently with any glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues.
2 Q8CD91 (/IDA) Q8CD91 (/IDA)
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2 Q8CD91 (/IDA) Q8CD91 (/IDA)
Extracellular matrix binding GO:0050840
Interacting selectively and non-covalently with a component of the extracellular matrix.
2 Q8BLY1 (/IDA) Q8BLY1 (/IDA)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
7 E7EDQ9 (/IMP) E7EDQ9 (/IMP) E7FH22 (/IMP) Q8BLY1 (/IMP) Q8BLY1 (/IMP) Q9H4F8 (/IMP) Q9H4F8 (/IMP)
Regulation of BMP signaling pathway GO:0030510
Any process that modulates the frequency, rate or extent of the activity of any BMP receptor signaling pathway.
6 A0A0R4IDK4 (/IMP) E7FET3 (/IMP) E7FET3 (/IMP) G9LQV9 (/IMP) G9LQV9 (/IMP) Q567B8 (/IMP)
Odontogenesis GO:0042476
The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food.
6 A0A0R4IDK4 (/IMP) E7FET3 (/IMP) E7FET3 (/IMP) G9LQV9 (/IMP) G9LQV9 (/IMP) Q567B8 (/IMP)
Embryonic viscerocranium morphogenesis GO:0048703
The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.
6 A0A0R4IDK4 (/IMP) E7FET3 (/IMP) E7FET3 (/IMP) G9LQV9 (/IMP) G9LQV9 (/IMP) Q567B8 (/IMP)
Myeloid cell development GO:0061515
The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure.
6 A0A0R4IDK4 (/IMP) E7FET3 (/IMP) E7FET3 (/IMP) G9LQV9 (/IMP) G9LQV9 (/IMP) Q567B8 (/IMP)
Positive regulation of cell-substrate adhesion GO:0010811
Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.
4 Q8BLY1 (/IDA) Q8BLY1 (/IDA) Q8CD91 (/IDA) Q8CD91 (/IDA)
Extracellular matrix organization GO:0030198
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
4 Q8BLY1 (/IDA) Q8BLY1 (/IDA) Q8CD91 (/IDA) Q8CD91 (/IDA)
Limb development GO:0060173
The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin.
4 Q8BLY1 (/IMP) Q8BLY1 (/IMP) Q9H4F8 (/IMP) Q9H4F8 (/IMP)
Optic cup morphogenesis involved in camera-type eye development GO:0002072
The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus.
3 E7EDQ9 (/IMP) E7EDQ9 (/IMP) E7FH22 (/IMP)
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
2 Q8BLY1 (/ISO) Q8BLY1 (/ISO)
Regulation of osteoblast differentiation GO:0045667
Any process that modulates the frequency, rate or extent of osteoblast differentiation.
2 Q9H4F8 (/IMP) Q9H4F8 (/IMP)
Regulation of osteoblast differentiation GO:0045667
Any process that modulates the frequency, rate or extent of osteoblast differentiation.
2 Q8BLY1 (/ISO) Q8BLY1 (/ISO)
Limb development GO:0060173
The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin.
2 Q8BLY1 (/ISO) Q8BLY1 (/ISO)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Basement membrane GO:0005604
A thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
4 Q8BLY1 (/IDA) Q8BLY1 (/IDA) Q8CD91 (/IDA) Q8CD91 (/IDA)
Proteinaceous extracellular matrix GO:0005578
A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity. An example of this component is found in Mus musculus.
2 Q8CD91 (/IDA) Q8CD91 (/IDA)
Interstitial matrix GO:0005614
A type of extracellular matrix found in interstitial connective tissue, characterized by the presence of fibronectins, proteoglycans, and types I, III, V, VI, VII and XII collagens.
2 Q8CD91 (/IDA) Q8CD91 (/IDA)