Generation of a long process from a neuron whose cell body resides in the peripheral nervous system. The axon carries action potential from the cell body towards target cells.

The aggregation, arrangement and bonding together of a set of components to form a protein complex.

The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.

A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.

The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).

Any process that activates or increases the rate or extent of cell proliferation.

The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system.

The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived.

The process in which the developmental fate of a cell becomes restricted such that it will develop into a glial cell.

The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium.

The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.

Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity.

Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.

The process in which a relatively unspecialized cell acquires specialized features of an auditory hair cell.

Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.

The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.

Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.

Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.

Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.

Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity.

A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state.

Any process that activates or increases the rate or extent of smooth muscle cell proliferation.

The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.

Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation.

Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation.

Any process that modulates the frequency, rate or extent of neurogenesis, the origin and formation of neurons.

Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.

Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation.

Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.

A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.

A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.

The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.

A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.

A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.

The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).

Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.

Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.

Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.

Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.

Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.

Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.

Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.

The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.

The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.

The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.

The process in which individual somites establish identity during embryogenesis.

The aggregation, arrangement and bonding together of a set of components to form a protein complex.

The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.

A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.

A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.

A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.

A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.

The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron.

The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).

Any process that activates or increases the rate or extent of cell proliferation.

Any process that activates or increases the rate or extent of cell proliferation.

The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.

The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system.

The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived.

The process in which the developmental fate of a cell becomes restricted such that it will develop into a glial cell.

The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.

The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium.

The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.

The process in which a relatively unspecialized cell acquires specialized features of a neuron.

Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity.

Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.

The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia.

The process in which a relatively unspecialized cell acquires specialized features of an auditory hair cell.

Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.

The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell regardless of its environment; upon determination, the cell fate cannot be reversed.

The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.

Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.

Any process that modulates the frequency, rate or extent of auditory hair cell differentiation.

Any process that modulates the frequency, rate or extent of neuron differentiation.

Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.

Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.

Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.

Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.

Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.

Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity.

A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state.

Any process that activates or increases the rate or extent of smooth muscle cell proliferation.

Any process that activates or increases the rate or extent of smooth muscle cell proliferation.

The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.

Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation.

Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation.

Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation.

Any process that modulates the frequency, rate or extent of epithelial cell proliferation.

Any process that modulates the frequency, rate or extent of neurogenesis, the origin and formation of neurons.

The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.

The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.

The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of inner ear receptor cells.

The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron.

The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron.

The process in which the loop of Henle of the kidney nephron acquires its identity.

The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros.

The specification and formation of anisotropic intracellular organization of an epithelial cell.

Any process in by an organism or tissue maintains a population of neuronal stem cells.

Any process in by an organism or tissue maintains a population of neuronal stem cells.

Any process in by an organism or tissue maintains a population of neuronal stem cells.

Any process in by an organism or tissue maintains a population of neuronal stem cells.

Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.

Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.

Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation.

Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation.

Any process that stops, prevents or reduces the frequency, rate or extent of inner ear receptor cell differentiation.

That part of the nuclear content other than the chromosomes or the nucleolus.

The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.