The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Helix-loop-helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5627: BHLH transcription factor PTF1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
22 A4D998 (/ISS) F4IQH8 (/ISS) O22768 (/ISS) Q0JXE7 (/ISS) Q3EAI1 (/ISS) Q6NKN9 (/ISS) Q8GWK7 (/ISS) Q8GY61 (/ISS) Q8GZ13 (/ISS) Q8S3D5 (/ISS)
(12 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 F4IQH8 (/IPI) Q6NKN9 (/IPI) Q8GWK7 (/IPI) Q8GY61 (/IPI) Q8GZ13 (/IPI) Q9C670 (/IPI) Q9FJL4 (/IPI)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
3 Q8GY61 (/IDA) Q8GZ13 (/IDA) Q93VJ4 (/IDA)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
2 Q9CAA9 (/IPI) Q9LV17 (/IPI)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
2 F4IQH8 (/IPI) Q9LK48 (/IPI)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1 Q8GY61 (/IDA)
BHLH transcription factor binding GO:0043425
Interacting selectively and non-covalently with any of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors, important regulatory components in transcriptional networks of many developmental pathways.
1 F4IQH8 (/IDA)

There are 21 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
19 A4D998 (/TAS) F4IQH8 (/TAS) O22768 (/TAS) Q0JXE7 (/TAS) Q3EAI1 (/TAS) Q6NKN9 (/TAS) Q8GWK7 (/TAS) Q8GZ13 (/TAS) Q8S3D5 (/TAS) Q8VZ02 (/TAS)
(9 more)
Response to blue light GO:0009637
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.
4 Q6NKN9 (/IDA) Q8GY61 (/IDA) Q9C670 (/IDA) Q9FJL4 (/IDA)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
3 Q8GWK7 (/IMP) Q8GZ13 (/IMP) Q93VJ4 (/IMP)
Root hair cell development GO:0080147
The process whose specific outcome is the progression of a root hair cell over time, from its formation to the mature state.
3 Q8S3D5 (/IMP) Q9LSQ3 (/IMP) Q9ZUG9 (/IMP)
Root hair cell differentiation GO:0048765
The process in which a relatively unspecialized cell acquires specialized features of a root hair cell.
2 Q8S3D5 (/IMP) Q9ZUG9 (/IMP)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
1 Q8GY61 (/IDA)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 A4D998 (/IMP)
MRNA transcription GO:0009299
The cellular synthesis of messenger RNA (mRNA) from a DNA template.
1 F4IQH8 (/IDA)
Double fertilization forming a zygote and endosperm GO:0009567
Fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana.
1 O22768 (/IMP)
Response to blue light GO:0009637
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.
1 Q8GY61 (/IEP)
Response to hormone GO:0009725
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
1 F4IQH8 (/IMP)
Response to cytokinin GO:0009735
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus.
1 F4IQH8 (/IEP)
Response to gibberellin GO:0009739
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus.
1 Q93W88 (/IEP)
Unidimensional cell growth GO:0009826
The process in which a cell irreversibly increases in size in one
1 F4IQH8 (/IMP)
Positive regulation of flower development GO:0009911
Any process that activates or increases the frequency, rate or extent of flower development.
1 Q9C670 (/IGI)
Positive regulation of flower development GO:0009911
Any process that activates or increases the frequency, rate or extent of flower development.
1 Q8GY61 (/IMP)
Regulation of defense response GO:0031347
Any process that modulates the frequency, rate or extent of a defense response.
1 O22768 (/IMP)
Petal morphogenesis GO:0048446
The process in which the anatomical structures of the petal are generated and organized.
1 Q0JXE7 (/IMP)
Root hair elongation GO:0048767
The process in which the root hair grows longer.
1 Q9ZUG9 (/IGI)
Positive regulation of shade avoidance GO:1902448
Any process that activates or increases the frequency, rate or extent of shade avoidance.
1 Q8GZ13 (/IMP)
Positive regulation of brassinosteroid biosynthetic process GO:2000488
Any process that activates or increases the frequency, rate or extent of brassinosteroid biosynthetic process.
1 A4D998 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
15 Q5N802 (/IC) Q5VR96 (/IC) Q69JJ6 (/IC) Q69WS3 (/IC) Q69Y51 (/IC) Q6EPZ6 (/IC) Q6Z2G7 (/IC) Q6Z7E7 (/IC) Q6ZCV8 (/IC) Q75M33 (/IC)
(5 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
7 A4D998 (/IDA) Q6NKN9 (/IDA) Q8GY61 (/IDA) Q8GZ13 (/IDA) Q9FJL4 (/IDA) Q9LSQ3 (/IDA) Q9ZUG9 (/IDA)