The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Helix-loop-helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1069: Myc protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
1 Q9W4S7 (/IDA)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1 Q9W4S7 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q9W4S7 (/IPI)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
1 Q9W4S7 (/IDA)

There are 35 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of cell growth GO:0001558
Any process that modulates the frequency, rate, extent or direction of cell growth.
1 Q9W4S7 (/IMP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 Q9W4S7 (/IDA)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 Q9W4S7 (/IMP)
Regulation of transcription from RNA polymerase III promoter GO:0006359
Any process that modulates the frequency, rate or extent of transcription from an RNA ploymerase III promoter.
1 Q9W4S7 (/IDA)
Regulation of transcription from RNA polymerase III promoter GO:0006359
Any process that modulates the frequency, rate or extent of transcription from an RNA ploymerase III promoter.
1 Q9W4S7 (/IPI)
Transcription from RNA polymerase I promoter GO:0006360
The synthesis of RNA from a DNA template by RNA polymerase I (RNAP I), originating at an RNAP I promoter.
1 Q9W4S7 (/IDA)
Cell proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
1 Q9W4S7 (/IEP)
Regulation of cell size GO:0008361
Any process that modulates the size of a cell.
1 Q9W4S7 (/TAS)
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
1 Q9W4S7 (/IEP)
Embryonic pattern specification GO:0009880
The process that results in the patterns of cell differentiation that will arise in an embryo.
1 Q9W4S7 (/IGI)
Regulation of autophagy GO:0010506
Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
1 Q9W4S7 (/IMP)
Regulation of glucose metabolic process GO:0010906
Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
1 Q9W4S7 (/IMP)
Neurogenesis GO:0022008
Generation of cells within the nervous system.
1 Q9W4S7 (/IGI)
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
1 Q9W4S7 (/TAS)
Cell competition in a multicellular organism GO:0035212
Competitive interactions within multicellular organisms between cell populations that differ in growth rates, leading to the elimination of the slowest-growing cells.
1 Q9W4S7 (/IMP)
Positive regulation of multicellular organism growth GO:0040018
Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
1 Q9W4S7 (/IMP)
Positive regulation of multicellular organism growth GO:0040018
Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
1 Q9W4S7 (/TAS)
DNA endoreduplication GO:0042023
Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes.
1 Q9W4S7 (/IMP)
Response to starvation GO:0042594
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
1 Q9W4S7 (/IMP)
Regulation of apoptotic process GO:0042981
Any process that modulates the occurrence or rate of cell death by apoptotic process.
1 Q9W4S7 (/IMP)
Regulation of imaginal disc-derived wing size GO:0044719
Any process that modulates the size of an imaginal disc-derived wing.
1 Q9W4S7 (/IMP)
Positive regulation of imaginal disc growth GO:0045572
Any process that activates or increases the frequency, rate or extent of imaginal disc growth.
1 Q9W4S7 (/IMP)
Negative regulation of Notch signaling pathway GO:0045746
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
1 Q9W4S7 (/IGI)
Positive regulation of cell size GO:0045793
Any process that increases cell size.
1 Q9W4S7 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 Q9W4S7 (/IMP)
Positive regulation of growth GO:0045927
Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism.
1 Q9W4S7 (/IMP)
Positive regulation of growth GO:0045927
Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism.
1 Q9W4S7 (/TAS)
Regulation of organ growth GO:0046620
Any process that modulates the frequency, rate or extent of growth of an organ of an organism.
1 Q9W4S7 (/IMP)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
1 Q9W4S7 (/TAS)
Positive regulation of developmental growth GO:0048639
Any process that activates, maintains or increases the rate of developmental growth.
1 Q9W4S7 (/IMP)
Positive regulation of neurogenesis GO:0050769
Any process that activates or increases the frequency, rate or extent of neurogenesis, the origin and formation of neurons.
1 Q9W4S7 (/IMP)
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
1 Q9W4S7 (/TAS)
Lipid homeostasis GO:0055088
Any process involved in the maintenance of an internal steady state of lipid within an organism or cell.
1 Q9W4S7 (/IMP)
Regulation of trehalose metabolic process GO:0090062
Any process that modulates the frequency, rate or extent of trehalose metabolism, the chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.
1 Q9W4S7 (/IMP)
Positive regulation of peptide hormone secretion GO:0090277
Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.
1 Q9W4S7 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein complex GO:0043234
A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
1 Q9W4S7 (/IPI)