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CATH Superfamily 4.10.1080.10

TSP type-3 repeat

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
TSP type-3 repeat
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2877: Alpha-agarase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Alpha-agarase. [EC: 3.2.1.158]
Endohydrolysis of 1,3-alpha-L-galactosidic linkages in agarose, yielding agarotetraose as the major product.
  • The enzyme from Thalassomonas sp. can use agarose, agarohexaose and neoagarohexaose as substrate.
  • The products of agarohexaose hydrolysis are dimers and tetramers, with agarotetraose being the predominant product, whereas hydrolysis of neoagarohexaose gives rise to two types of trimer.
  • While the enzyme can also hydrolyze the highly sulfated agarose porphyran very efficiently, it cannot hydrolyze kappa-carrageenan and iota-carrageenan.
 1 A1IGV8