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CATH Superfamily 3.90.950.10

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5699: Non-canonical purine NTP pyrophosphatase

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Nucleotide diphosphatase. [EC: 3.6.1.9]
A nucleoside triphosphate + H(2)O = a nucleotide + diphosphate.
  • The enzyme preferentially hydrolyzes ATP, but can also hydrolyze other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates.
  • In vitro the enzyme also acts as a nucleotidohydrolase on ADP, NAD(+), NADP(+), FAD, and CoA.
  • Formerly EC 3.6.1.19.
 1434 A0A015JJZ2 A0A016VEY9 A0A016VFQ1 A0A016VGI6 A0A017STF0 A0A022R1D6 A0A022VUR9 A0A022W1S5 A0A022XKQ9 A0A022XSV9
(1424 more...)
Transferred entry: 3.6.1.9. [EC: 3.6.1.19]
    		61 A0A023B7I1 A0A062WVY6 A0A075ATN7 A0A075FZU8 A0A075G915 A0A075GF07 A0A075GM66 A0A075GPS7 A0A075GT49 A0A075GXV5
    (51 more...)
    Nucleoside-triphosphate phosphatase. [EC: 3.6.1.15]
    NTP + H(2)O = NDP + phosphate.
    • The enzyme is found in eukaryotes and thermophilic bacteria, but appears to be absent from mesophilic bacteria.
    • Also hydrolyzes nucleoside diphosphates, thiamine diphosphate and FAD.
    • The enzyme from the plant Pisum sativum (garden pea) is regulated by calmodulin.
    		 13 A0A075ATN7 A0A0A8RK07 A0A0E3MM78 A0A167S6J9 D1JHN9 D6YQW2 F7PNV3 I7KZK4 L7JTV2 L7YAM0
    (3 more...)
    XTP/dITP diphosphatase. [EC: 3.6.1.66]
    (1) XTP + H(2)O = XMP + diphosphate. (2) dITP + H(2)O = dIMP + diphosphate.
    • The enzymes from the bacterium Escherichia coli and the archaea Methanococcus jannaschii and Archaeoglobus fulgidus are highly specific for XTP and dITP.
    		 2 A0A1D8S6U8 A0A1J1AE48
    Ribonuclease P. [EC: 3.1.26.5]
    Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.
    • Essential for tRNA processing; generates 5'-termini of mature tRNA molecules.
    		 1 G4D5W6