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CATH Superfamily 3.90.79.10

Nucleoside Triphosphate Pyrophosphohydrolase

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Nucleoside Triphosphate Pyrophosphohydrolase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9648: Nudix hydrolase superfamily protein

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
8-oxo-dGTP diphosphatase. [EC: 3.6.1.55]
8-oxo-dGTP + H(2)O = 8-oxo-dGMP + diphosphate.
  • This enzyme hydrolyzes the phosphoanhydride bond between the alpha and beta phosphate of 8-oxoguanine-containing nucleoside di- and triphosphates thereby preventing misincorporation of the oxidized purine nucleoside triphosphates into DNA.
  • It does not hydrolyze 2-hydroxy-dATP (cf. EC 3.6.1.56).
 69 A0A024DFU2 A0A081QYE1 A0A081SCR1 A0A0B7GQS7 A0A0B7LCP3 A0A0B7LS82 A0A0E2P476 A0A0E9H159 A0A0F2D384 A0A0H2ZN52
(59 more...)
Dihydroorotase. [EC: 3.5.2.3]
(S)-dihydroorotate + H(2)O = N-carbamoyl-L-aspartate.
    		 34 A0A024DFU2 A0A081QYE1 A0A0F2D384 A0A125YWC6 A0A1E9GKF2 A0A1F0AU08 A0A1F0BMF3 A0A1F0N6L1 A0A1F1EQD6 A4L7L7
    (24 more...)
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