The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Nucleoside Triphosphate Pyrophosphohydrolase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 21468: ADP compounds hydrolase NudE

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
ADP-ribose diphosphatase. [EC: 3.6.1.13]
ADP-D-ribose + H(2)O = AMP + D-ribose 5-phosphate.
    51 A0A026RZQ7 A0A029HGN6 A0A029IJJ3 A0A090NCH8 A0A0A7A0I0 A0A0B2W7S2 A0A0E1CC05 A0A0E2L004 A0A0G3J0X9 A0A0G3JLF2
    (41 more...)
    NAD(+) diphosphatase. [EC: 3.6.1.22]
    NAD(H) + H(2)O = AMP + NMN(H).
    • This enzyme, described from plants, animals, and bacteria, can act on both reduced and oxidized forms of its substrate, although enzymes from different organisms have different preferences.
    • Also acts on other dinucleotides, including NADP(H), FAD(H(2)), and the thionicotinamide analogs of NAD(+) and NADP(+).
    50 A0A026RZQ7 A0A029HGN6 A0A029IJJ3 A0A090NCH8 A0A0A7A0I0 A0A0E1CC05 A0A0E2L004 A0A0G3J0X9 A0A0G3JLF2 A0A0H2VD43
    (40 more...)
    Bis(5'-adenosyl)-triphosphatase. [EC: 3.6.1.29]
    P(1)-P(3)-bis(5'-adenosyl) triphosphate + H(2)O = ADP + AMP.
      50 A0A026RZQ7 A0A029HGN6 A0A029IJJ3 A0A090NCH8 A0A0A7A0I0 A0A0E1CC05 A0A0E2L004 A0A0G3J0X9 A0A0G3JLF2 A0A0H2VD43
      (40 more...)
      ADP-sugar diphosphatase. [EC: 3.6.1.21]
      ADP-sugar + H(2)O = AMP + alpha-D-aldose 1-phosphate.
      • Has a distinct specificity from EC 3.6.1.45.
      1 A0A085U715
      CATH-Gene3D is a Global Biodata Core Resource Learn more...