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CATH Superfamily 3.90.79.10

Nucleoside Triphosphate Pyrophosphohydrolase

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Nucleoside Triphosphate Pyrophosphohydrolase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12433: NTP pyrophosphohydrolase (MutT) (7,8-dihydro-8-oxo...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
8-oxo-dGTP diphosphatase. [EC: 3.6.1.55]
8-oxo-dGTP + H(2)O = 8-oxo-dGMP + diphosphate.
  • This enzyme hydrolyzes the phosphoanhydride bond between the alpha and beta phosphate of 8-oxoguanine-containing nucleoside di- and triphosphates thereby preventing misincorporation of the oxidized purine nucleoside triphosphates into DNA.
  • It does not hydrolyze 2-hydroxy-dATP (cf. EC 3.6.1.56).
 13 A0A0C5F6N9 A0A0E1SQI0 A0A0H3PPB7 A0A0K9L0M4 A0A110KF95 A0A121Y0J2 A0A158SV93 A4MWC6 A4N1I6 A5UI52
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