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CATH Superfamily 3.90.70.10

Cysteine proteinases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Cysteine proteinases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 17205: Ubiquitin carboxyl-terminal hydrolase 16

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Deleted entry. [EC: 3.1.2.15]
    		19 A0A074SXR4 A0A086JIN0 A0A086JTR2 A0A086LSA2 A0A086PSI5 A0A086QNY2 A0A0J5PWY2 A0A125YRG4 A0A125YRG5 A0A151H9E4
    (9 more...)
    Ubiquitinyl hydrolase 1. [EC: 3.4.19.12]
    Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
    • Links to polypeptides smaller than 60 residues are hydrolyzed more readily than those to larger polypeptides.
    • Isoforms exist with quantitatively different specificities among the best known being UCH-L1 and UCH-L3, major proteins of the brain of mammals.
    • Inhibited by ubiquitin aldehyde (in which Gly76 is replaced by aminoacetaldehyde).
    • Belongs to peptidase family C12.
    		 11 A0A0F4YUI6 A0A0R3P1D0 B3MZV5 B3NUP8 B4L5I7 B4PWG5 B5DNL3 N1PA89 P25037 Q9UUD6
    (1 more...)
    H(+)-transporting two-sector ATPase. [EC: 3.6.3.14]
    ATP + H(2)O + H(+)(In) = ADP + phosphate + H(+)(Out).
    • A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.
    • Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (F(o), V(o), A(o)) and a cytoplasmic-compartment sector (F(1), V(1), A(1)).
    • The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.
    • All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.
    • Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.
    • This movement is driven by the H(+) electrochemical potential gradient.
    • The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.
    • Formerly EC 3.6.1.34.
    		 1 G0QZC6
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