The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Cysteine proteinases
".
FunFam 16912: Ubiquitin carboxyl-terminal hydrolase 37
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cysteine-type endopeptidase activity GO:0004197
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
|
6 | E1C213 (/ISS) E2RK09 (/ISS) E7F6T8 (/ISS) F1N5V1 (/ISS) F1SRY5 (/ISS) Q8C0R0 (/ISS) |
|
Thiol-dependent ubiquitin-specific protease activity GO:0004843
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
|
6 | E1C213 (/ISS) E2RK09 (/ISS) E7F6T8 (/ISS) F1N5V1 (/ISS) F1SRY5 (/ISS) Q8C0R0 (/ISS) |
|
Thiol-dependent ubiquitinyl hydrolase activity GO:0036459
Catalysis of the thiol-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bond formed by the C-terminal glycine of ubiquitin.
|
3 | Q86T82 (/TAS) Q9BXU7 (/TAS) Q9HBJ7 (/TAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q86T82 (/IPI) Q9BXU7 (/IPI) |
|
Cysteine-type endopeptidase activity GO:0004197
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
|
1 | Q86T82 (/IDA) |
|
Cysteine-type endopeptidase activity GO:0004197
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
|
1 | Q8C0R0 (/ISO) |
|
Thiol-dependent ubiquitin-specific protease activity GO:0004843
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
|
1 | Q86T82 (/IDA) |
|
Thiol-dependent ubiquitin-specific protease activity GO:0004843
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
|
1 | Q8C0R0 (/ISO) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | Q86T82 (/IPI) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | Q8C0R0 (/ISO) |
There are 18 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
G1/S transition of mitotic cell cycle GO:0000082
The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
|
6 | E1C213 (/ISS) E2RK09 (/ISS) E7F6T8 (/ISS) F1N5V1 (/ISS) F1SRY5 (/ISS) Q8C0R0 (/ISS) |
|
Protein K11-linked deubiquitination GO:0035871
A protein deubiquitination process in which a K11-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 11 of the ubiquitin monomers, is removed from a protein.
|
6 | E1C213 (/ISS) E2RK09 (/ISS) E7F6T8 (/ISS) F1N5V1 (/ISS) F1SRY5 (/ISS) Q8C0R0 (/ISS) |
|
Protein K48-linked deubiquitination GO:0071108
A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein.
|
6 | E1C213 (/ISS) E2RK09 (/ISS) E7F6T8 (/ISS) F1N5V1 (/ISS) F1SRY5 (/ISS) Q8C0R0 (/ISS) |
|
Regulation of DNA replication GO:0006275
Any process that modulates the frequency, rate or extent of DNA replication.
|
4 | E2RK09 (/ISS) F1N5V1 (/ISS) F1SRY5 (/ISS) Q8C0R0 (/ISS) |
|
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
4 | E2RK09 (/ISS) F1N5V1 (/ISS) F1SRY5 (/ISS) Q8C0R0 (/ISS) |
|
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
2 | Q86T82 (/IDA) Q9BXU7 (/IDA) |
|
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
2 | Q8C0R0 (/ISO) Q99MX1 (/ISO) |
|
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
2 | Q86T82 (/TAS) Q9BXU7 (/TAS) |
|
G1/S transition of mitotic cell cycle GO:0000082
The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
|
1 | Q86T82 (/IDA) |
|
G1/S transition of mitotic cell cycle GO:0000082
The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
|
1 | Q8C0R0 (/ISO) |
|
Regulation of DNA replication GO:0006275
Any process that modulates the frequency, rate or extent of DNA replication.
|
1 | Q86T82 (/IMP) |
|
Regulation of DNA replication GO:0006275
Any process that modulates the frequency, rate or extent of DNA replication.
|
1 | Q8C0R0 (/ISO) |
|
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
1 | Q86T82 (/IMP) |
|
Central nervous system morphogenesis GO:0021551
The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
|
1 | E7F6T8 (/IMP) |
|
Protein K11-linked deubiquitination GO:0035871
A protein deubiquitination process in which a K11-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 11 of the ubiquitin monomers, is removed from a protein.
|
1 | Q86T82 (/IDA) |
|
Protein K11-linked deubiquitination GO:0035871
A protein deubiquitination process in which a K11-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 11 of the ubiquitin monomers, is removed from a protein.
|
1 | Q8C0R0 (/ISO) |
|
Protein K48-linked deubiquitination GO:0071108
A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein.
|
1 | Q86T82 (/IDA) |
|
Protein K48-linked deubiquitination GO:0071108
A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein.
|
1 | Q8C0R0 (/ISO) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q86T82 (/IDA) Q9BXU7 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q8C0R0 (/ISO) Q99MX1 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | Q86T82 (/TAS) Q9BXU7 (/TAS) |