The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
PurM-like C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8781: Phosphoribosylformylglycinamidine cyclo-ligase, ch...

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phosphoribosylformylglycinamidine cyclo-ligase. [EC: 6.3.3.1]
ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.
    643 A0A010PRZ5 A0A010ZG83 A0A016WCH0 A0A023D0L3 A0A023F128 A0A023FKK3 A0A023GMB6 A0A024P4V0 A0A026X2D7 A0A034VBM4
    (633 more...)
    Phosphoribosylglycinamide formyltransferase. [EC: 2.1.2.2]
    10-formyltetrahydrofolate + N(1)-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide.
      127 A0A016WCH0 A0A023F128 A0A023FKK3 A0A023GMB6 A0A026X2D7 A0A034VBM4 A0A087ZR29 A0A0A1WVA5 A0A0A9WHI9 A0A0B2V3P5
      (117 more...)
      Phosphoribosylamine--glycine ligase. [EC: 6.3.4.13]
      ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N(1)- (5-phospho-D-ribosyl)glycinamide.
      • Formerly EC 6.3.1.3.
      127 A0A016WCH0 A0A023F128 A0A023FKK3 A0A023GMB6 A0A026X2D7 A0A034VBM4 A0A087ZR29 A0A0A1WVA5 A0A0A9WHI9 A0A0B2V3P5
      (117 more...)