The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
PurM-like C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8452: Trifunctional purine biosynthetic protein adenosin...

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phosphoribosylformylglycinamidine cyclo-ligase. [EC: 6.3.3.1]
ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.
    8 B4GJZ2 B4HY19 B4NZX2 B4Q5B4 F3YDH3 P00967 P16340 X2J516
    Phosphoribosylglycinamide formyltransferase. [EC: 2.1.2.2]
    10-formyltetrahydrofolate + N(1)-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide.
      8 B4GJZ2 B4HY19 B4NZX2 B4Q5B4 F3YDH3 P00967 P16340 X2J516
      Phosphoribosylamine--glycine ligase. [EC: 6.3.4.13]
      ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N(1)- (5-phospho-D-ribosyl)glycinamide.
      • Formerly EC 6.3.1.3.
      8 B4GJZ2 B4HY19 B4NZX2 B4Q5B4 F3YDH3 P00967 P16340 X2J516