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CATH Superfamily 3.90.550.10

Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 64684: Beta-1,4-galactosyltransferase 3,4-related

There are 7 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
N-acetyllactosamine synthase. [EC: 2.4.1.90]
UDP-alpha-D-galactose + N-acetyl-D-glucosamine = UDP + N-acetyllactosamine.
  • The reaction is catalyzed by a component of EC 2.4.1.22, which is identical with EC 2.4.1.38, and by an enzyme from the Golgi apparatus of animal tissues.
  • Formerly EC 2.4.1.98.
 60 A0A061I5N1 A0A061I5N1 B1ASJ2 B1ASJ2 B2RAZ5 B2RAZ5 B7PHD9 B7PHD9 B7PJI3 B7PJI3
(50 more...)
Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase. [EC: 2.4.1.38]
UDP-alpha-D-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide.
  • Terminal N-acetyl-beta-D-glucosaminyl residues in polysaccharides, glycoproteins and glycopeptides can act as acceptor.
  • High activity is shown toward such residues in branched-chain polysaccharides when these are linked by beta-1,6 links to galactose residues; lower activity toward residues linked to galactose by beta- 1,3 links.
  • A component of EC 2.4.1.22.
 42 B1ASJ2 B1ASJ2 G3HFF7 G3HFF7 G3HU17 G3HU17 G4VNW8 G4VNW8 G4VT32 G4VT32
(32 more...)
Lactose synthase. [EC: 2.4.1.22]
UDP-alpha-D-galactose + D-glucose = UDP + lactose.
  • The enzyme is a complex of 2 proteins A and B.
  • In the absence of the B protein (alpha-lactalbumin) the enzyme catalyzes the transfer of galactose from UDP-galactose to N-acetylglucosamine (cf. EC 2.4.1.90).
 24 B1ASJ2 B1ASJ2 C1KH59 C1KH59 G3HFF7 G3HFF7 G4VNW8 G4VNW8 G4VT32 G4VT32
(14 more...)
Glucosylceramide beta-1,4-galactosyltransferase. [EC: 2.4.1.274]
UDP-alpha-D-galactose + beta-D-glucosyl-(1<->1)-ceramide = UDP + beta-D- galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide.
  • Involved in the synthesis of several different major classes of glycosphingolipids.
 14 A0A061ID44 A0A061ID44 A0A061IJR6 A0A061IJR6 H2NW49 H2NW49 O88419 O88419 Q3UUA9 Q3UUA9
(4 more...)
Neolactotriaosylceramide beta-1,4-galactosyltransferase. [EC: 2.4.1.275]
UDP-alpha-D-galactose + N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D- galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide = UDP + beta-D- galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl- (1->4)-beta-D-glucosyl-(1<->1)-ceramide.
    		 12 B2RAZ5 B2RAZ5 G3I1K4 G3I1K4 O60513 O60513 Q66HH1 Q66HH1 Q80WN7 Q80WN7
    (2 more...)
    N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase. [EC: 2.4.1.244]
    UDP-N-acetyl-alpha-D-galactosamine + N-acetyl-beta-D-glucosaminyl group = UDP + N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl group.
    • The enzyme from human can transfer N-acetyl-D-galactosamine (GalNAc) to N-glycan and O-glycan substrates that have N-acetyl-D-glucosamine (GlcNAc) but not D-glucuronic acid (GlcUA) at their non-reducing end.
    • The N-acetyl-beta-D-glucosaminyl group is normally on a core oligosaccharide although benzyl glycosides have been used in enzyme- characterization experiments.
    • Some glycohormones, e.g. lutropin and thyrotropin contain the N-glycan structure containing the N-acetyl-beta-D-galactosaminyl- (1->4)-N-acetyl-beta-D-glucosaminyl group.
    		 2 Q7KN92 Q7KN92
    Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase. [EC: 2.4.1.135]
    UDP-alpha-D-glucuronate + [protein]-3-O-(beta-D-galactosyl-(1->3)-beta-D- galactosyl-(1->4)-beta-D-xylosyl)-L-serine = UDP + [protein]-3-O-(beta-D- GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine.
    • Involved in the biosynthesis of the linkage region of glycosaminoglycan chains as part of proteoglycan biosynthesis (chondroitin, dermatan and heparan sulfates).
    		 2 M7BZW0 M7BZW0