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CATH Superfamily 3.90.550.10

Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 56063: Glycosyl transferase, family 2

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase. [EC: 2.4.2.53]
UDP-4-deoxy-4-formamido-beta-L-arabinose + ditrans,octacis-undecaprenyl phosphate = UDP + 4-deoxy-4-formamido-alpha-L-arabinose ditrans,octacis- undecaprenyl phosphate.
  • The enzyme shows no activity with UDP-4-amino-4-deoxy-beta-L- arabinose.
  • Formerly EC 2.7.8.30 and EC 2.7.8.n1.
 4 A0A0H2M7A1 A0A158BNL2 A0A158BX26 A0A158DUL7
Dolichyl-phosphate beta-D-mannosyltransferase. [EC: 2.4.1.83]
GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate.
  • Acts only on long-chain polyprenyl phosphates and alpha- dihydropolyprenyl phosphates, larger than C(35).
 3 A0A0A0FDA5 A0A173KQS8 E1SGS4
Undecaprenyl-phosphate mannosyltransferase. [EC: 2.4.1.54]
GDP-alpha-D-mannose + undecaprenyl phosphate = GDP + D-mannosyl-1- phosphoundecaprenol.
  • Requires phosphatidylglycerol.
 2 A0A158C226 A0A158EKU1
Glucosyl-3-phosphoglycerate synthase. [EC: 2.4.1.266]
NDP-glucose + 3-phospho-D-glycerate = NDP + 2-O-(alpha-D-glucopyranosyl)- 3-phospho-D-glycerate.
  • The enzyme is involved in biosynthesis of 2-O-(alpha-D- glucopyranosyl)-D-glycerate via the two-step pathway in which glucosyl-3-phosphoglycerate synthase catalyzes the conversion of GDP- glucose and 3-phospho-D-glycerate into 2-O-(alpha-D-glucopyranosyl)- 3-phospho-D-glycerate, which is then converted to 2-O-(alpha-D- glucopyranosyl)-D-glycerate by EC 3.1.3.85.
  • The activity is dependent on divalent cations (Mn(2+), Co(2+), or Mg(2+)).
  • The enzyme from Persephonella marina shows moderate flexibility on the sugar donor concerning the nucleotide moiety (UDP-glucose, ADP- glucose, GDP-glucose) but is strictly specific for glucose.
  • The enzyme is also strictly specific for 3-phospho-D-glycerate as acceptor.
  • The enzyme from Methanococcoides burtonii is strictly specific for GDP-glucose and 3-phospho-D-glycerate.
  • This enzyme catalyzes the first glucosylation step in methylglucose lipopolysaccharide biosynthesis in mycobacteria.
 2 A0A1E2ZI63 A0A1E7WSM2