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CATH Superfamily 3.90.190.10

Protein tyrosine phosphatase superfamily

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Protein tyrosine phosphatase superfamily
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11685: Dual specificity phosphatase, catalytic

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Protein-tyrosine-phosphatase. [EC: 3.1.3.48]
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
  • Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.
 146 A0A023B5S0 A0A023B5S0 A0A024VYJ6 A0A024VYJ6 A0A060RZV2 A0A060RZV2 A0A088RJ44 A0A088RJ44 A0A088S7Z0 A0A088S7Z0
(136 more...)
Protein-serine/threonine phosphatase. [EC: 3.1.3.16]
[a protein]-serine/threonine phosphate + H(2)O = [a protein]- serine/threonine + phosphate.
  • A group of enzymes removing the serine- or threonine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase (cf. EC 3.1.3.48).
  • The spleen enzyme also acts on phenolic phosphates and phosphamides (cf. EC 3.9.1.1).
 136 A0A023B5S0 A0A023B5S0 A0A024VYJ6 A0A024VYJ6 A0A060RZV2 A0A060RZV2 A0A060TGI2 A0A060TGI2 A0A074T4P2 A0A074T4P2
(126 more...)
4-nitrophenylphosphatase. [EC: 3.1.3.41]
4-nitrophenyl phosphate + H(2)O = 4-nitrophenol + phosphate.
  • A number of other substances, including phenyl phosphate, 4-nitrophenyl sulfate, acetyl phosphate and glycerol phosphate, are not substrates.
 2 Q9VWF4 Q9VWF4
Glycylpeptide N-tetradecanoyltransferase. [EC: 2.3.1.97]
Tetradecanoyl-CoA + glycylpeptide = CoA + N-tetradecanoylglycylpeptide.
  • The enzyme from Saccharomyces cerevisiae is highly specific for tetradecanoyl-CoA, and for N-terminal glycine in oligopeptides containing serine in the 5-position.
  • The enzyme from mammalian heart transfers acyl groups to a specific acceptor protein of 51 kDa.
 2 G0R686 G0R686
1-phosphatidylinositol-3-phosphate 5-kinase. [EC: 2.7.1.150]
ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate = ADP + 1-phosphatidyl- 1D-myo-inositol 3,5-bisphosphate.
    		 2 G0R686 G0R686
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