The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Protein tyrosine phosphatase superfamily
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11650: Dual-specificity protein-like phosphatase 1

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Protein-serine/threonine phosphatase. [EC: 3.1.3.16]
[a protein]-serine/threonine phosphate + H(2)O = [a protein]- serine/threonine + phosphate.
  • A group of enzymes removing the serine- or threonine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase (cf. EC 3.1.3.48).
  • The spleen enzyme also acts on phenolic phosphates and phosphamides (cf. EC 3.9.1.1).
15 A0A0B2NX82 A0A0B2PL49 A0A0B2SGD5 A0A178VTK4 B5RJ36 B7QAW4 B9RD15 B9RKE9 B9SZP8 I1K0T6
(5 more...)
Protein-tyrosine-phosphatase. [EC: 3.1.3.48]
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
  • Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.
12 A0A0Q9WP77 A0A178VTK4 B3LY53 B4K5B0 B4M0F7 B4NG46 B4PNX4 B5RJ36 D3TQZ2 Q299C8
(2 more...)
Phosphatidylglycerophosphatase. [EC: 3.1.3.27]
Phosphatidylglycerophosphate + H(2)O = phosphatidylglycerol + phosphate.
    2 B5RJ36 Q86BN8
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