View in Gene3D

CATH Superfamily 3.90.190.10

Protein tyrosine phosphatase superfamily

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Protein tyrosine phosphatase superfamily
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 11623: Myotubularin related protein 4

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Protein-tyrosine-phosphatase. [EC: 3.1.3.48]
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
  • Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.
 10 A0A061I1E1 A0A061IGH4 A0A061IHI3 A0A061IK09 A0A061IL59 Q13615 Q5PQT2 Q8K296 Q91XS1 Q9NYA4
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase. [EC: 3.1.3.95]
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H(2)O = 1-phosphatidyl- 1D-myo-inositol 5-phosphate + phosphate.
  • The enzyme is found in both plants and animals.
  • It also has the activity of EC 3.1.3.64.
 3 Q13615 Q5PQT2 Q8K296
Phosphatidylinositol-3-phosphatase. [EC: 3.1.3.64]
1-phosphatidyl-1D-myo-inositol 3-phosphate + H(2)O = 1-phosphatidyl- 1D-myo-inositol + phosphate.
  • This enzyme still works when the 2,3-bis(acyloxy)propyl group is removed, i.e., it hydrolyzes Ins(1,3)P(2) to Ins-1-P.
  • Formerly EC 3.1.3.65.
 3 Q13615 Q5PQT2 Q8K296
CATH-Gene3D is a Global Biodata Core Resource Learn more...