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CATH Superfamily 3.90.180.10

Medium-chain alcohol dehydrogenases, catalytic domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Medium-chain alcohol dehydrogenases, catalytic domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 33923: Quinone oxidoreductase, YhdH/YhfP family

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Alcohol dehydrogenase. [EC: 1.1.1.1]
(1) An alcohol + NAD(+) = an aldehyde or ketone + NADH. (2) A secondary alcohol + NAD(+) = a ketone + NADH.
  • Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.
  • The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.
 18 A0A084ZS61 A0A085GPB9 A0A085IM00 A0A085UAV5 A0A0H7HIG0 A0A0M3HEK7 A0A157URH3 A0A1B1NK24 C2HSX1 C9XTH2
(8 more...)
Acrylyl-CoA reductase (NADPH). [EC: 1.3.1.84]
Propanoyl-CoA + NADP(+) = acrylyl-CoA + NADPH.
  • Catalyzes a step in the 3-hydroxypropanoate/4-hydroxybutyrate cycle, an autotrophic CO(2) fixation pathway found in some thermoacidophilic archaea.
  • The reaction is catalyzed in the opposite direction to that shown.
  • The enzyme from Sulfolobus tokodaii does not act on either NADH or crotonyl-CoA.
  • Different from EC 1.3.1.8, which acts only on enoyl-CoA derivatives of carbon chain length 4 to 16.
 5 A0A085UAV5 A0A1L9I6D7 Q3J6K9 Q5LS56 W7P3H6