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CATH Superfamily 3.90.1200.10

Aminoglycoside phosphotransferase (APH), C-terminal lobe

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8080: Fusion protein, Feo

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Kanamycin kinase. [EC: 2.7.1.95]
ATP + kanamycin = ADP + kanamycin 3'-phosphate.
  • Also acts on the antibiotics neomycin, paromomycin, neamine, paromamine, vistamycin and gentamicin A.
  • An enzyme from Pseudomonas aeruginosa also acts on butirosin.
 30 A0A060V9V2 A0A068DRS3 A0A084SQA4 A0A0C3I4F5 A0A0K2CTV4 A0A140WY25 A0A149VWA2 A0A193CJY5 A0A1C2A141 A0A1E7VS11
(20 more...)
Streptomycin 3''-kinase. [EC: 2.7.1.87]
ATP + streptomycin = ADP + streptomycin 3''-phosphate.
  • Also phosphorylates dihydrostreptomycin, 3'-deoxydihydrostreptomycin and their 6-phosphates.
 25 A0A060V9V2 A0A068DRS3 A0A084SQA4 A0A0C3I4F5 A0A0K2CTV4 A0A140WY25 A0A1C2A141 A0A1G4DZ73 A0A1J6ZR26 A6V7P0
(15 more...)
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